CHO-K1/Rat 5-HT1D Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0003C | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
The 5-HT1D receptor is a G protein-coupled receptor (GPCR) that functions as a serotonin-activated GPCR. It is involved in the adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, leading to reduced intracellular cAMP levels, and participates in the regulation of intestinal smooth muscle contraction. As an integral component of the plasma membrane, it plays a key role in transducing extracellular signals into intracellular responses.
Screeningbio’s CHO-K1/Rat 5-HT1D cell line overexpress rat HTR1D and is designed to detect inhibition in intracellular cAMP levels in response to agonist stimulation of the receptor. Cisbio HTRF cAMP kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Rat |
HGNC Symbol | 5-HT1D |
Accession Number | NM_012852 (Rn) |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
The 5-HT1D receptor is a G protein-coupled receptor (GPCR) that functions as a serotonin-activated GPCR. It is involved in the adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, leading to reduced intracellular cAMP levels, and participates in the regulation of intestinal smooth muscle contraction. As an integral component of the plasma membrane, it plays a key role in transducing extracellular signals into intracellular responses.