CHO-K1/Human 5-HT1F Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0005A | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
The 5-HT1F receptor belongs to the G protein-coupled receptor family and is highly homologous to the 5-HT1D and 5-HT1E receptors. This receptor is primarily expressed in brain regions such as the hippocampus, cortex, and raphe nuclei, and is involved in the regulation of neurotransmission and emotional processes. Studies have shown that abnormalities in the expression and function of the HTR1F gene may be associated with the pathogenesis of psychiatric disorders such as depression and anxiety, and therefore its role in related psychopathological research is increasingly being recognized.
Screeningbio’s CHO-K1/Human 5-HT1F cell line overexpress HTR1F and is designed to detect inhibition in intracellular cAMP levels in response to agonist stimulation of the receptor. Cisbio HTRF cAMP kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Human |
HGNC Symbol | 5-HT1F |
Accession Number | NM_000866 |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
The 5-HT1F receptor belongs to the G protein-coupled receptor family and is highly homologous to the 5-HT1D and 5-HT1E receptors. This receptor is primarily expressed in brain regions such as the hippocampus, cortex, and raphe nuclei, and is involved in the regulation of neurotransmission and emotional processes. Studies have shown that abnormalities in the expression and function of the HTR1F gene may be associated with the pathogenesis of psychiatric disorders such as depression and anxiety, and therefore its role in related psychopathological research is increasingly being recognized.