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ScreeNingBio's Target Protein Degradation Solution:
Ready-To-Go Assay and Cell Lines
Comprehensive TPD Coverage
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Ready-to-use cell lines (HiBit KI, Nano-Luc KI, POI-NanoLuc OE, NanoBRET Ternary Cell Line) and assay kits (TR-FRET) tailored for Targeted Protein Degradation (TPD), covering diverse E3 ligases and disease-relevant targets.
Advanced Ternary Complex Assays
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Robust TR-FRET and BRET binding platforms optimized to evaluate cooperative ternary complex formation (“POI-PROTAC-E3 Ligase”) with high sensitivity and reproducibility
Custom Cell Line Engineering
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Custom stable cell generation leveraging advanced CRISPR knock-in technologies (such as HiBiT and NanoLuc tags) for real-time target degradation monitoring

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