HEK293/Hman B1 Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0038A | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
The bradykinin B1 receptor is a G protein-coupled receptor that is primarily induced during inflammation or tissue injury. It is significantly upregulated on immune cells (such as macrophages and neutrophils) and vascular smooth muscle. Its functions include mediating vasodilation, increasing vascular permeability, promoting pain signal transmission, and regulating inflammatory responses, playing a critical role in pathological processes like chronic pain, sepsis, and arthritis.
Screeningbio’s HEK293/Human B1 cell line overexpress BDKRB1 and is designed to detect increases in intracellular Calcium flux signal in response to agonist stimulation of the receptor. Molecular Devices Calcium 6 kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Human |
HGNC Symbol | B1 |
Accession Number | NM_000710 |
Parental Line | HEK293 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
The bradykinin B1 receptor is a G protein-coupled receptor that is primarily induced during inflammation or tissue injury. It is significantly upregulated on immune cells (such as macrophages and neutrophils) and vascular smooth muscle. Its functions include mediating vasodilation, increasing vascular permeability, promoting pain signal transmission, and regulating inflammatory responses, playing a critical role in pathological processes like chronic pain, sepsis, and arthritis.