Product Description

The β2-adrenergic receptor (β2-AR) is an important member of the G protein-coupled receptor family and plays a broad role in regulating physiological processes such as cardiovascular function, respiratory control, and metabolic processes. This receptor is crucial in modulating airway smooth muscle tone, and its dysregulation is closely associated with the development and progression of various diseases, including nocturnal asthma, obesity, type 2 diabetes, and cardiovascular diseases. Due to its significant physiological functions, current drug development targeting the β2 receptor primarily focuses on creating novel agonists and antagonists, offering new therapeutic strategies for respiratory diseases, tumors, and other disorders.

Screeningbio’s CHO-K1/Rat β2-adrenoceptor cell line overexpress rat ADRB2 and is designed to detect increases in intracellular cAMP levels in response to agonist stimulation of the receptor. Cisbio HTRF cAMP kit can be used to detect the signal.