CHO-K1/Rat P2Y1 Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0180C | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
The P2Y1 receptor is a G protein-coupled receptor activated by ADP, belonging to the purinergic receptor family. It is primarily expressed on platelets, vascular endothelial cells, vascular smooth muscle cells, and in certain regions of the central nervous system. Its core function is to mediate rapid ADP-induced platelet aggregation, initiating physiological hemostasis and playing a crucial role in arterial thrombosis. Additionally, it participates in regulating vascular tone, endothelial function, and neural signaling, making it a key molecule in the development of antithrombotic drugs.
Screeningbio’s CHO-K1/Rat P2Y1 cell line overexpress rat P2RY1 receptor and is designed to detect increases in intracellular IP-1 levels in response to agonist stimulation of the receptor. Cisbio HTRF IP-1 kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Rat |
HGNC Symbol | P2Y1 |
Accession Number | SNB-G-0180C |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
The P2Y1 receptor is a G protein-coupled receptor activated by ADP, belonging to the purinergic receptor family. It is primarily expressed on platelets, vascular endothelial cells, vascular smooth muscle cells, and in certain regions of the central nervous system.
Its core function is to mediate rapid ADP-induced platelet aggregation, initiating physiological hemostasis and playing a crucial role in arterial thrombosis. Additionally, it participates in regulating vascular tone, endothelial function, and neural signaling, making it a key molecule in the development of antithrombotic drugs.