top of page

CHO-K1/Rat NMU1 Stable Cell

Item
Cat#
Price

Stable Cell Line

SNB-G-0159C

$19,800

Compound Testing Services

CT-001

$1,850 per 384w plate

(Up To 16 cpds Dose)


Product Description


Neuromedin U receptor 1 (NMU1) is a G protein-coupled receptor primarily expressed in the central nervous system (such as the hypothalamus) and the gastrointestinal tract. Its key functions include regulating feeding behavior, energy balance, gastrointestinal motility, and stress responses. Upon activation by its ligand neuromedin U, NMU1 modulates various physiological processes through downstream signaling pathways, playing a significant role in obesity, metabolism, and digestive system function.

 

Screeningbio’s CHO-K1/Rat NMU1 cell line overexpress NMU1 receptor and is designed to detect increases in intracellular IP-1 levels in response to agonist stimulation of the receptor. Cisbio HTRF IP-1 kit can be used to detect the signal.

Product Specifications

Target Type

GPCR

Species

Rat

HGNC Symbol

NMUR1

Accession Number

SNB-G-0159C

Parental Line

CHO-K1

Lot#

See Vial

Storage

Liquid Nitrogen


Data


CHO-K1/Rat NMU1 Agonist Assay. CHO-K1/Rat NMU1 cells were treated with the reference agonist. The assay was run based on Revvity IP-one HTRF protocol. Non-linear regression was used to plot activity changes vs. [Compound, M], and EC50 /IC50 values were determined, using GraphPad Prism software.
CHO-K1/Rat NMU1 Agonist Assay. CHO-K1/Rat NMU1 cells were treated with the reference agonist. The assay was run based on Revvity IP-one HTRF protocol. Non-linear regression was used to plot activity changes vs. [Compound, M], and EC50 /IC50 values were determined, using GraphPad Prism software.


Target Background


Neuromedin U receptor 1 (NMU1) is a G protein-coupled receptor primarily expressed in the central nervous system (such as the hypothalamus) and the gastrointestinal tract.


Its key functions include regulating feeding behavior, energy balance, gastrointestinal motility, and stress responses.


Upon activation by its ligand neuromedin U, NMU1 modulates various physiological processes through downstream signaling pathways, playing a significant role in obesity, metabolism, and digestive system function.

Product Documentation



bottom of page