CHO-K1/Mouse NPFF1 Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0161B | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
Neuropeptide FF receptor 1 (NPFF1) is a G protein-coupled receptor primarily distributed in the central nervous system, especially in regions associated with pain perception and neuroendocrine regulation such as the spinal cord, brainstem, and hypothalamus. Its main functions include modulating pain sensation, particularly mediating thermal and inflammatory pain, and exerting anti-opioid effects. Additionally, it is involved in regulating cardiovascular activity, feeding, and stress responses, serving as a key receptor for mediating the physiological and pharmacological effects of neuropeptide FF.
Screeningbio’s CHO-K1/Mouse NPFF1 cell line overexpress NPFFR1 and is designed to detect inhibition in intracellular cAMP levels in response to agonist stimulation of the receptor. Cisbio HTRF cAMP kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Mouse |
HGNC Symbol | NPFF1 receptor |
Accession Number | SNB-G-0161B |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
Neuropeptide FF receptor 1 (NPFF1) is a G protein-coupled receptor primarily distributed in the central nervous system, especially in regions associated with pain perception and neuroendocrine regulation such as the spinal cord, brainstem, and hypothalamus.
Its main functions include modulating pain sensation, particularly mediating thermal and inflammatory pain, and exerting anti-opioid effects. Additionally, it is involved in regulating cardiovascular activity, feeding, and stress responses, serving as a key receptor for mediating the physiological and pharmacological effects of neuropeptide FF.