CHO-K1/Human Y1 Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0166A | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
The neuropeptide Y receptor Y1 is a G protein-coupled receptor that binds neuropeptide Y. It is primarily distributed in the brain (e.g., hypothalamus, amygdala) and peripheral regions such as the cardiovascular system, kidneys, and adipose tissue. Its core function is to mediate diverse physiological effects of NPY, including stimulating feeding behavior, modulating anxiety and stress responses, promoting vasoconstriction, and participating in energy metabolism and fat storage. It plays a significant regulatory role in conditions like obesity, mood disorders, and hypertension. dulation of inflammatory pain, and emotions.
Screeningbio’s CHO-K1/Human Y1 cell line overexpress NPY1R and is designed to detect inhibition in intracellular cAMP levels in response to agonist stimulation of the receptor. Cisbio HTRF cAMP kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Human |
HGNC Symbol | NPY1R |
Accession Number | SNB-G-0166A |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
The neuropeptide Y receptor Y1 is a G protein-coupled receptor that binds neuropeptide Y. It is primarily distributed in the brain (e.g., hypothalamus, amygdala) and peripheral regions such as the cardiovascular system, kidneys, and adipose tissue.
Its core function is to mediate diverse physiological effects of NPY, including stimulating feeding behavior, modulating anxiety and stress responses, promoting vasoconstriction, and participating in energy metabolism and fat storage.
It plays a significant regulatory role in conditions like obesity, mood disorders, and hypertension. dulation of inflammatory pain, and emotions.