CHO-K1/Human GPR17(long form) Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0236A | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
GPR17 is an orphan receptor belonging to the class A G protein-coupled receptor (GPCR) family. It is primarily expressed in the central nervous system and immune system, where it participates in the development and functional regulation of glial cells. This receptor acts as a sensor for focal myelination damage and contributes to the repair of demyelinated plaques caused by inflammatory processes. As a result, GPR17 is regarded as a potential therapeutic target for promoting remyelination in neurodegenerative diseases such as multiple sclerosis.
Screeningbio’s CHO-K1/Human GPR17 Gq cell line overexpress GPR17 receptor and is designed to detect increases in intracellular Calcium flux signal in response to agonist stimulation of the receptor. Molecular Devices Calcium 6 kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Human |
HGNC Symbol | GPR17 |
Accession Number | NM_005291 (Hs) |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
GPR17 is an orphan receptor belonging to the class A G protein-coupled receptor (GPCR) family. It is primarily expressed in the central nervous system and immune system, where it participates in the development and functional regulation of glial cells.
This receptor acts as a sensor for focal myelination damage and contributes to the repair of demyelinated plaques caused by inflammatory processes. As a result, GPR17 is regarded as a potential therapeutic target for promoting remyelination in neurodegenerative diseases such as multiple sclerosis.