CHO-K1/Cyno MRGPRX2 Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0270S | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
MRGPRX2 (Mas-related G protein-coupled receptor member X2) is a G protein-coupled receptor (GPCR) primarily expressed in mast cells and certain neural tissues. It is involved in various physiological and pathological processes, including pain sensation, immune responses, and inflammation. The neuro-immune hyperactivation mediated by MRGPRX2 is a common feature of many chronic diseases, such as allergy, autoimmunity, pain, and pruritus.
Screeningbio’s CHO-K1/Cyno MRGPRX2 cell line overexpress MRGPRX2 receptor and is designed to detect increases in intracellular Calcium flux signal in response to agonist stimulation of the receptor. Molecular Devices Calcium 6 kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Macaca fascicularis (Cyno) |
HGNC Symbol | MRGPRX2 |
Accession Number | XM_015435307.3 |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
MRGPRX2 (Mas-related G protein-coupled receptor member X2) is a G protein-coupled receptor (GPCR) primarily expressed in mast cells and certain neural tissues. It is involved in various physiological and pathological processes, including pain sensation, immune responses, and inflammation.
The neuro-immune hyperactivation mediated by MRGPRX2 is a common feature of many chronic diseases, such as allergy, autoimmunity, pain, and pruritus.