top of page

CHO-K1/Rhesus GIPR Stable Cell

Item
Cat#
Price

Stable Cell Line

SNB-G-0103T

$19,800

Compound Testing Services

CT-001

$1,850 per 384w plate

(Up To 16 cpds Dose)


Product Description


The Gastric Inhibitory Polypeptide Receptor (GIPR) is a class B G protein-coupled receptor (GPCR) that mediates the physiological actions of the incretin hormone GIP, primarily involved in glucose homeostasis and lipid metabolism. GIPR is predominantly expressed in pancreatic β-cells, adipose tissue, and the central nervous system, where it plays a key role in enhancing insulin secretion in response to nutrient intake.

 

Screeningbio’s CHO-K1/Rhesus GIPR cell line overexpress GIPR and is designed to detect increases in intracellular cAMP levels in response to agonist stimulation of the receptor. Cisbio HTRF cAMP kit xcan be used to detect the signal.

Product Specifications

Target Type

GPCR

Species

Rhesus

HGNC Symbol

GIPR

Accession Number

XM_028838699.1 (Rhesus)

Parental Line

CHO-K1

Lot#

See Vial

Storage

Liquid Nitrogen


Data

CHO-K1/Rhesus GIPR Agonist Assay. CHO-K1/Rhesus GIPR cells were treated with the reference agonist. The assay was run based on Revvity cAMP HTRF protocol. Non-linear regression was used to plot activity changes vs. [Compound, M], and EC50 values were determined, using GraphPad Prism software.
CHO-K1/Rhesus GIPR Agonist Assay. CHO-K1/Rhesus GIPR cells were treated with the reference agonist. The assay was run based on Revvity cAMP HTRF protocol. Non-linear regression was used to plot activity changes vs. [Compound, M], and EC50 values were determined, using GraphPad Prism software.


Target Background


The Gastric Inhibitory Polypeptide Receptor (GIPR) is a class B G protein-coupled receptor (GPCR) that mediates the physiological actions of the incretin hormone GIP, primarily involved in glucose homeostasis and lipid metabolism.



GIPR is predominantly expressed in pancreatic β-cells, adipose tissue, and the central nervous system, where it plays a key role in enhancing insulin secretion in response to nutrient intake.

Product Documentation



Screeningbio

For research use only. All rights reserved. Not for use in diagnostic procedures, human or veterinary treatment, food, cosmetics, or household applications. ScreeningBio provides laboratory research products and R&D services to qualified research organizations. We do not sell pharmaceuticals, dietary supplements, or products intended for human consumption.

6181 Cornerstone Ct, Suite 102, San Diego, CA 92121, USA

Quick Links

Connect

  • Facebook
  • Twitter
  • LinkedIn

CHINA: 上海格宁生物

info@screeningbio.com

4th Floor, Building 24, No.1188 Lianhang Road Minhang District, Shanghai, China

bottom of page