CHO-K1/Rat NPFF2 Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0162C | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
Neuropeptide FF receptor 2 (NPFF2) is a member of the G protein-coupled receptor family, predominantly distributed in the central nervous system with notable expression in regions associated with emotion, endocrine regulation, and pain modulation, such as the hippocampus, hypothalamus, and spinal dorsal horn. Its core functions involve modulating opioid system activity, influencing pain processing, opioid tolerance, and addiction, as well as participating in blood pressure regulation, stress responses, and energy balance. NPFF2 serves as a key receptor mediating the anti-opioid or modulatory effects of neuropeptide FF on endogenous opioid actions.
Screeningbio’s CHO-K1/Rat NPFF2 cell line overexpress NPFFR2 and is designed to detect inhibition in intracellular cAMP levels in response to agonist stimulation of the receptor. Cisbio HTRF cAMP kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Rat |
HGNC Symbol | NPFF2 receptor |
Accession Number | SNB-G-0162C |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
Neuropeptide FF receptor 2 (NPFF2) is a member of the G protein-coupled receptor family, predominantly distributed in the central nervous system with notable expression in regions associated with emotion, endocrine regulation, and pain modulation, such as the hippocampus, hypothalamus, and spinal dorsal horn.
Its core functions involve modulating opioid system activity, influencing pain processing, opioid tolerance, and addiction, as well as participating in blood pressure regulation, stress responses, and energy balance. NPFF2 serves as a key receptor mediating the anti-opioid or modulatory effects of neuropeptide FF on endogenous opioid actions.