CHO-K1/Mouse NMU2 Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0160B | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
Neuromedin U receptor 2 (NMU2) is a high-affinity receptor for neuromedin U and also a G protein-coupled receptor. It is predominantly distributed in the central nervous system, particularly in specific brain regions such as the hypothalamus, with low expression levels in peripheral tissues. Its core functions include potently suppressing appetite, regulating energy homeostasis and body weight, and involvement in stress responses and circadian rhythm modulation. NMU2 is considered the primary mediator for the key anorexigenic and metabolic regulatory effects of neuromedin U.
Screeningbio’s CHO-K1/Mouse NMU2 cell line overexpress NMU2 receptor and is designed to detect increases in intracellular IP-1 levels in response to agonist stimulation of the receptor. Cisbio HTRF IP-1 kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Mouse |
HGNC Symbol | NMUR2 |
Accession Number | SNB-G-0160B |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
Neuromedin U receptor 2 (NMU2) is a high-affinity receptor for neuromedin U and also a G protein-coupled receptor. It is predominantly distributed in the central nervous system, particularly in specific brain regions such as the hypothalamus, with low expression levels in peripheral tissues.
Its core functions include potently suppressing appetite, regulating energy homeostasis and body weight, and involvement in stress responses and circadian rhythm modulation. NMU2 is considered the primary mediator for the key anorexigenic and metabolic regulatory effects of neuromedin U.