CHO-K1/Human MRGPRD Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0265A | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
MRGPRD (Mas-related G-protein coupled receptor member D) is a G protein-coupled receptor primarily expressed in specific non-peptidergic sensory neurons of the dorsal root ganglia in mice. Its function is to recognize endogenous ligands such as β-alanine, playing a crucial role in specifically mediating chemical heat pain perception and regulating pathological pain sensitization. It is also potentially involved in chronic pain and neurogenic inflammation processes, making it a novel potential target for analgesic drugs.
Screeningbio’s CHO-K1/Human MRGPRD cell line overexpress MRGPRD receptor and is designed to detect increases in intracellular Calcium flux signal in response to agonist stimulation of the receptor. Molecular Devices Calcium 6 kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Human |
HGNC Symbol | MRGPRD |
Accession Number | SNB-G-0265A |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
MRGPRD (Mas-related G-protein coupled receptor member D) is a G protein-coupled receptor primarily expressed in specific non-peptidergic sensory neurons of the dorsal root ganglia in mice.
Its function is to recognize endogenous ligands such as β-alanine, playing a crucial role in specifically mediating chemical heat pain perception and regulating pathological pain sensitization. It is also potentially involved in chronic pain and neurogenic inflammation processes, making it a novel potential target for analgesic drugs.