CHO-K1/Human APJ β-Arrestin Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-A-0033A | Inquiry |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
The Apelin receptor (APLNR) is a member of the class A G protein-coupled receptor family. It is widely expressed throughout the body in various organs and tissues, including the brain, heart, liver, kidneys, lungs, stomach, uterus, testes, adipose tissue, skin, limbs, placenta, as well as the central nervous and cardiovascular systems. This receptor and its ligands are involved in numerous physiological functions and pathophysiological processes, making it a critical potential therapeutic target for diseases such as ischemic heart disease, hypertension, and heart failure.
Screeningbio’s CHO-K1/Human Apelin cell line overexpress APLNR and is designed to detect decreases in intracellular cAMP levels in response to agonist stimulation of the receptor. Cisbio HTRF cAMP kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Human |
HGNC Symbol | APLNR |
Accession Number | NM_005161 |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
The Apelin receptor (APLNR) is a member of the class A G protein-coupled receptor family. It is widely expressed throughout the body in various organs and tissues, including the brain, heart, liver, kidneys, lungs, stomach, uterus, testes, adipose tissue, skin, limbs, placenta, as well as the central nervous and cardiovascular systems.
This receptor and its ligands are involved in numerous physiological functions and pathophysiological processes, making it a critical potential therapeutic target for diseases such as ischemic heart disease, hypertension, and heart failure.