COR-L23/R Drug Resistance Cell
Item | Cat# | Price |
Drug Resistance Cell | SNB-TC-0145 | Inquiry |
Compound Test Services | CT-002 | Inquiry |
Product Description
The cell line COR-L23/R is a multi-drug resistant (MDR) sub-line derived from the parent line COR-L23 after treatment with doxorubicin (adriamycin). The P-glycoprotein negative cell line is cross resistant to daunorubicin, vincristine and rhodamine 123. COR-L23/R contain reduced levels of glutathione and glutathione-S-transferase activity compared to the parent line.
Screeningbio‘s COR-L23/R resistance cell line generated by exposing to increasing concentration of drug for certain period of time. After stable acquire resistance, cells were harvested and characterized for drug resistance by 7 days proliferation assay.
Data
Target Background
The cell line COR-L23/R is a multi-drug resistant (MDR) sub-line derived from the parent line COR-L23 after treatment with doxorubicin (adriamycin). The P-glycoprotein negative cell line is cross resistant to daunorubicin, vincristine and rhodamine 123. COR-L23/R contain reduced levels of glutathione and glutathione-S-transferase activity compared to the parent line.
Screeningbio‘s COR-L23/R resistance cell line generated by exposing to increasing concentration of drug for certain period of time. After stable acquire resistance, cells were harvested and characterized for drug resistance by 7 days proliferation assay.