CHO-K1/Rat α1A-adrenoceptor Stable Cell
Item | Cat# | Price |
Stable Cell Line | SNB-G-0022C | $19,800 |
Compound Testing Services | CT-001 | $1,850 per 384w plate (Up To 16 cpds Dose) |
Product Description
The α1A-adrenoceptor is a predominantly postsynaptic G protein-coupled receptor that is widely expressed in various smooth muscle tissues throughout the body, including those in the eyes, lungs, blood vessels, uterus, intestines, and urogenital system. Activation of this receptor induces smooth muscle contraction, leading to a range of physiological responses such as mydriasis (pupil dilation), bronchoconstriction, vasoconstriction, uterine contraction, and contraction of the gastrointestinal and urogenital sphincters.
Screeningbio’s CHO-K1/Rat α1A-adrenoceptor cell line overexpress rat ADRA1A receptor and is designed to detect increases in intracellular IP-1 levels in response to agonist stimulation of the receptor. Cisbio HTRF IP-1 kit can be used to detect the signal.
Product Specifications
Target Type | GPCR |
Species | Rat |
HGNC Symbol | α1A-adrenoceptor |
Accession Number | NM_017191 |
Parental Line | CHO-K1 |
Lot# | See Vial |
Storage | Liquid Nitrogen |
Data
Target Background
The α1A-adrenoceptor is a predominantly postsynaptic G protein-coupled receptor that is widely expressed in various smooth muscle tissues throughout the body, including those in the eyes, lungs, blood vessels, uterus, intestines, and urogenital system.
Activation of this receptor induces smooth muscle contraction, leading to a range of physiological responses such as mydriasis (pupil dilation), bronchoconstriction, vasoconstriction, uterine contraction, and contraction of the gastrointestinal and urogenital sphincters.