核受体 (Nuclear Receptor)

 

Nuclear receptors (NR) are intracellular transcription factors that directly regulate gene expression in response to lipophilic molecules, they affect a wide variety of functions, including fatty acid metabolism, reproductive development, and detoxification of foreign substances.

 

Humans have 48 nuclear receptors, which when dysregulated are often linked to diseases. Because most nuclear receptors can be selectively activated or inactivated by small molecules, they are prominent therapeutic targets.

ScreeNingBio’s offer the nucleare receptors stable cell lines to support your drug R&D activity

-   Reporter assay
-   Cell line stablility up to 20 passages

Your target not in SNB list yet? Please contact info@screeningbio.com